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Human LEFTY2 activation kit by CRISPRa

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SKU
GA104851
LEFTY2 CRISPRa kit - CRISPR gene activation of human left-right determination factor 2
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA350490 Rabbit Polyclonal Anti-LEFTY2 Antibody
100 ul
$205.00
RC207799 LEFTY2 (Myc-DDK-tagged)-Human left-right determination factor 2 (LEFTY2), transcript variant 1
10 ug
$457.00

Other products for "LEFTY2"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol LEFTY2
Locus ID 7044
Components

GA104851G1, LEFTY2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA104851G2, LEFTY2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA104851G3, LEFTY2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001172425, NM_003240
UniProt ID O00292
Synonyms EBAF; LEFTA; LEFTYA; TGFB4
Summary This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate the mature protein, which plays a role in left-right asymmetry determination of organ systems during development. The protein may also play a role in endometrial bleeding. Mutations in this gene have been associated with left-right axis malformations, particularly in the heart and lungs. Some types of infertility have been associated with dysregulated expression of this gene in the endometrium. This gene is closely linked to both a related family member and a related pseudogene. This gene encodes multiple isoforms that may undergo similar proteolytic processing. provided by RefSeq, Aug 2016
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Documents
Resources
Other Versions
SKU Description Size Price
KN407799 LEFTY2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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