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Human TCF7 activation kit by CRISPRa

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SKU
GA104783
TCF7 CRISPRa kit - CRISPR gene activation of human transcription factor 7
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA366829 TCF7 rabbit polyclonal antibody
100 ul
$310.00
RC224338 TCF7 (Myc-DDK-tagged)-Human transcription factor 7 (T-cell specific, HMG-box) (TCF7), transcript variant 4
10 ug
$300.00

Other products for "TCF7"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol TCF7
Locus ID 6932
Components

GA104783G1, TCF7 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA104783G2, TCF7 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA104783G3, TCF7 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001134851, NM_001134852, NM_003202, NM_201632, NM_201633, NM_201634, NM_213648, NR_033449, NM_001346425, NM_001346450, NM_001366502
UniProt ID P36402
Synonyms TCF-1
Summary This gene encodes a member of the T-cell factor/lymphoid enhancer-binding factor family of high mobility group (HMG) box transcriptional activators. This gene is expressed predominantly in T-cells and plays a critical role in natural killer cell and innate lymphoid cell development. The encoded protein forms a complex with beta-catenin and activates transcription through a Wnt/beta-catenin signaling pathway. Mice with a knockout of this gene are viable and fertile, but display a block in T-lymphocyte differentiation. Alternative splicing results in multiple transcript variants. Naturally-occurring isoforms lacking the N-terminal beta-catenin interaction domain may act as dominant negative regulators of Wnt signaling. provided by RefSeq, Oct 2016
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Documents
Resources
Other Versions
SKU Description Size Price
KN407918 TCF7 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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