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Human ELOB activation kit by CRISPRa

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SKU
GA104776
ELOB CRISPRa kit - CRISPR gene activation of human elongin B
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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100 ul
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RC201393 TCEB2 (Myc-DDK-tagged)-Human transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B) (TCEB2), transcript variant 1
10 ug
$150.00

Other products for "ELOB"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol ELOB
Locus ID 6923
Components

GA104776G1, ELOB gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA104776G2, ELOB gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA104776G3, ELOB gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_007108, NM_207013
UniProt ID Q15370
Synonyms ELOB; SIII
Summary This gene encodes the protein elongin B, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. Pseudogenes have been identified on chromosomes 11 and 13. provided by RefSeq, Aug 2008
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Documents
Resources
Other Versions
SKU Description Size Price
KN401393 TCEB2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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