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Human Stromal interaction molecule 1 (STIM1) activation kit by CRISPRa

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SKU
GA104672
STIM1 CRISPRa kit - CRISPR gene activation of human stromal interaction molecule 1
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA306421 Rabbit Polyclonal STIM1 Antibody
100 ug
$640.00
RC205678 STIM1 (Myc-DDK-tagged)-Human stromal interaction molecule 1 (STIM1)
10 ug
$941.00

Other products for "STIM1"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol STIM1
Locus ID 6786
Components

GA104672G1, Stromal interaction molecule 1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA104672G2, Stromal interaction molecule 1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA104672G3, Stromal interaction molecule 1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001277961, NM_001277962, NM_003156
UniProt ID Q13586
Synonyms D11S4896E; GOK; IMD10; STRMK; TAM; TAM1
Summary This gene encodes a type 1 transmembrane protein that mediates Ca2+ influx after depletion of intracellular Ca2+ stores by gating of store-operated Ca2+ influx channels (SOCs). It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region, as well as early hematopoiesis, by mediating attachment to stromal cells. Mutations in this gene are associated with fatal classic Kaposi sarcoma, immunodeficiency due to defects in store-operated calcium entry (SOCE) in fibroblasts, ectodermal dysplasia and tubular aggregate myopathy. This gene is oriented in a head-to-tail configuration with the ribonucleotide reductase 1 gene (RRM1), with the 3' end of this gene situated 1.6 kb from the 5' end of the RRM1 gene. Alternative splicing of this gene results in multiple transcript variants. provided by RefSeq, May 2013
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Documents
Resources
Other Versions
SKU Description Size Price
KN405678 STIM1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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