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Human STAT5B activation kit by CRISPRa

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SKU
GA104664
STAT5B CRISPRa kit - CRISPR gene activation of human signal transducer and activator of transcription 5B
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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100 ul
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RC209429 STAT5B (Myc-DDK-tagged)-Human signal transducer and activator of transcription 5B (STAT5B)
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Other products for "STAT5B"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol STAT5B
Locus ID 6777
Components

GA104664G1, STAT5B gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA104664G2, STAT5B gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA104664G3, STAT5B gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_012448
UniProt ID P51692
Synonyms STAT5
Summary The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL). The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL. provided by RefSeq, Jul 2008
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Documents
Resources
Other Versions
SKU Description Size Price
KN409429 STAT5B - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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