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Human SPTBN2 activation kit by CRISPRa

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SKU
GA104611
SPTBN2 CRISPRa kit - CRISPR gene activation of human spectrin beta, non-erythrocytic 2
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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100 ul
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RC222257 SPTBN2 (Myc-DDK-tagged)-Human spectrin, beta, non-erythrocytic 2 (SPTBN2)
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Other products for "SPTBN2"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol SPTBN2
Locus ID 6712
Components

GA104611G1, SPTBN2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA104611G2, SPTBN2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA104611G3, SPTBN2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_006946
UniProt ID O15020
Synonyms GTRAP41; SCA5; SCAR14
Summary Spectrins are principle components of a cell's membrane-cytoskeleton and are composed of two alpha and two beta spectrin subunits. The protein encoded by this gene (SPTBN2), is called spectrin beta non-erythrocytic 2 or beta-III spectrin. It is related to, but distinct from, the beta-II spectrin gene which is also known as spectrin beta non-erythrocytic 1 (SPTBN1). SPTBN2 regulates the glutamate signaling pathway by stabilizing the glutamate transporter EAAT4 at the surface of the plasma membrane. Mutations in this gene cause a form of spinocerebellar ataxia, SCA5, that is characterized by neurodegeneration, progressive locomotor incoordination, dysarthria, and uncoordinated eye movements. provided by RefSeq, Dec 2009
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Documents
Resources
Other Versions
SKU Description Size Price
KN422257 SPTBN2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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