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Human SNRPN activation kit by CRISPRa

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SKU
GA104550
SNRPN CRISPRa kit - CRISPR gene activation of human small nuclear ribonucleoprotein polypeptide N
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA349164 Rabbit Polyclonal Anti-SNRPN Antibody
100 ug
$640.00
RC220680 SNRPN (Myc-DDK-tagged)-Human small nuclear ribonucleoprotein polypeptide N (SNRPN), transcript variant 2
10 ug
$300.00

Other products for "SNRPN"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol SNRPN
Locus ID 6638
Components

GA104550G1, SNRPN gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA104550G2, SNRPN gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA104550G3, SNRPN gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_003097, NM_022805, NM_022806, NM_022807, NM_022808, NM_001349454, NM_001349455, NM_001349456, NM_001349457, NM_001349458, NM_001349459, NM_001349460, NM_001349461, NM_001349462, NM_001349463, NM_001349464, NM_001349465
UniProt ID P63162
Synonyms HCERN3; PWCR; PWS; RT-LI; SM-D; sm-N; SMN; SNRNP-N; SNURF-SNRPN
Summary This gene is located within the Prader-Willi Syndrome critical region on chromosome 15 and is imprinted and expressed from the paternal allele. It encodes a component of the small nuclear ribonucleoprotein complex, which functions in pre-mRNA processing and may contribute to tissue-specific alternative splicing. Alternative promoter use and alternative splicing result in a multitude of transcript variants encoding the same protein. Transcript variants that initiate at the CpG island-associated imprinting center may be bicistronic and also encode the SNRPN upstream reading frame protein (SNURF) from an upstream open reading frame. In addition, long spliced transcripts for small nucleolar RNA host gene 14 (SNHG14) may originate from the promoters at this locus and share exons with this gene. Alterations in this region are associated with parental imprint switch failure, which may cause Angelman syndrome or Prader-Willi syndrome. provided by RefSeq, Mar 2017
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Documents
Resources
Other Versions
SKU Description Size Price
KN416279 SNRPN - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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