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Human SLC12A3 activation kit by CRISPRa

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SKU
GA104479
SLC12A3 CRISPRa kit - CRISPR gene activation of human solute carrier family 12 member 3
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA367635 SLC12A3 rabbit polyclonal antibody
100 ul
$310.00
RC221919 SLC12A3 (Myc-DDK-tagged)-Human solute carrier family 12 (sodium/chloride transporters), member 3 (SLC12A3), transcript variant 1
10 ug
$897.00

Other products for "SLC12A3"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol SLC12A3
Locus ID 6559
Components

GA104479G1, SLC12A3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA104479G2, SLC12A3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA104479G3, SLC12A3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_000339, NM_001126107, NM_001126108
UniProt ID P55017
Synonyms NCC; NCCT; TSC
Summary This gene encodes a renal thiazide-sensitive sodium-chloride cotransporter that is important for electrolyte homeostasis. This cotransporter mediates sodium and chloride reabsorption in the distal convoluted tubule. Mutations in this gene cause Gitelman syndrome, a disease similar to Bartter's syndrome, that is characterized by hypokalemic alkalosis combined with hypomagnesemia, low urinary calcium, and increased renin activity associated with normal blood pressure. This cotransporter is the target for thiazide diuretics that are used for treating high blood pressure. Multiple transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Jul 2008
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Documents
Resources
Other Versions
SKU Description Size Price
KN421919 SLC12A3 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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