Human SH3BP2 activation kit by CRISPRa

SKU
GA104393
SH3BP2 CRISPRa kit - CRISPR gene activation of human SH3 domain binding protein 2
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol SH3BP2
Locus ID 6452
Components

GA104393G1, SH3BP2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA104393G2, SH3BP2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA104393G3, SH3BP2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001122681, NM_001145855, NM_001145856, NM_003023
UniProt ID P78314
Synonyms 3BP-2; 3BP2; CRBM; CRPM; RES4-23
Summary The protein encoded by this gene has an N-terminal pleckstrin homology (PH) domain, an SH3-binding proline-rich region, and a C-terminal SH2 domain. The protein binds to the SH3 domains of several proteins including the ABL1 and SYK protein tyrosine kinases , and functions as a cytoplasmic adaptor protein to positively regulate transcriptional activity in T, natural killer (NK), and basophilic cells. Mutations in this gene result in cherubism. Multiple transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Mar 2009
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Documents
Resources
Other Versions
SKU Description Size Price
KN405759 SH3BP2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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