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Human MEK4 (MAP2K4) activation kit by CRISPRa

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SKU
GA104363
MAP2K4 CRISPRa kit - CRISPR gene activation of human mitogen-activated protein kinase kinase 4
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA500403 Anti-MAP2K4 (MEK4) mouse monoclonal antibody, clone OTI8A8 (formerly 8A8) 100 ul
$447.00
RC206051 MAP2K4 (Myc-DDK-tagged)-Human mitogen-activated protein kinase kinase 4 (MAP2K4)
10 ug
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Other products for "MAP2K4"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol MAP2K4
Locus ID 6416
Components

GA104363G1, MEK4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA104363G2, MEK4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA104363G3, MEK4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001281435, NM_003010
UniProt ID P45985
Synonyms JNKK; JNKK1; MAPKK4; MEK4; MKK4; PRKMK4; SAPKK-1; SAPKK1; SEK1; SERK1; SKK1
Summary This gene encodes a member of the mitogen-activated protein kinase (MAPK) family. Members of this family act as an integration point for multiple biochemical signals and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development. They form a three-tiered signaling module composed of MAPKKKs, MAPKKs, and MAPKs. This protein is phosphorylated at serine and threonine residues by MAPKKKs and subsequently phosphorylates downstream MAPK targets at threonine and tyrosine residues. A similar protein in mouse has been reported to play a role in liver organogenesis. A pseudogene of this gene is located on the long arm of chromosome X. Alternative splicing results in multiple transcript variants. provided by RefSeq, Jul 2013
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Documents
Resources
Other Versions
SKU Description Size Price
KN406051 MAP2K4 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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