Human Eotaxin 2 (CCL24) activation kit by CRISPRa

SKU
GA104331
CCL24 CRISPRa kit - CRISPR gene activation of human C-C motif chemokine ligand 24
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol CCL24
Locus ID 6369
Components

GA104331G1, Eotaxin 2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA104331G2, Eotaxin 2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA104331G3, Eotaxin 2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_002991
UniProt ID O00175
Synonyms Ckb-6; MPIF-2; MPIF2; SCYA24
Summary This gene belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity on resting T lymphocytes, a minimal activity on neutrophils, and is negative on monocytes and activated T lymphocytes. This protein also has antimicrobial activity, displaying an antibacterial effect on S. pneumoniae, S. aureus, Non-typeable H. influenzae, and P. aeruginosa. Finally, the protein is a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. provided by RefSeq, Jul 2020
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Documents
Resources
Other Versions
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KN220724 CCL24 - human gene knockout kit via CRISPR, HDR mediated 1 kit
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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