Human CCL3 activation kit by CRISPRa

SKU GA104313

CCL3 CRISPRa kit - CRISPR gene activation of human C-C motif chemokine ligand 3

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: CCL3
• Locus ID: 6348
• Components:

  GA104313G1, CCL3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104313G2, CCL3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104313G3, CCL3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_002983
• UniProt ID: P10147
• Synonyms: G0S19-1; LD78ALPHA; MIP-1-alpha; MIP1A; SCYA3
• Summary: This locus represents a small inducible cytokine. The encoded protein, also known as macrophage inflammatory protein 1 alpha, plays a role in inflammatory responses through binding to the receptors CCR1, CCR4 and CCR5. Polymorphisms at this locus may be associated with both resistance and susceptibility to infection by human immunodeficiency virus type 1.[provided by RefSeq, Sep 2010]