Human Nav1.6 (SCN8A) activation kit by CRISPRa

SKU
GA104299
SCN8A CRISPRa kit - CRISPR gene activation of human sodium voltage-gated channel alpha subunit 8
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol SCN8A
Locus ID 6334
Components

GA104299G1, Nav1.6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA104299G2, Nav1.6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA104299G3, Nav1.6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001177984, NM_014191, NM_001330260, NM_001369788
UniProt ID Q9UQD0
Synonyms CERIII; CIAT; EIEE13; MED; NaCh6; Nav1.6; PN4
Summary This gene encodes a member of the sodium channel alpha subunit gene family. The encoded protein forms the ion pore region of the voltage-gated sodium channel. This protein is essential for the rapid membrane depolarization that occurs during the formation of the action potential in excitable neurons. Mutations in this gene are associated with cognitive disability, pancerebellar atrophy and ataxia. Alternate splicing results in multiple transcript variants.provided by RefSeq, May 2010
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Other Versions
SKU Description Size Price
KN423887 SCN8A - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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