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Human SCN1B activation kit by CRISPRa

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SKU
GA104291
SCN1B CRISPRa kit - CRISPR gene activation of human sodium voltage-gated channel beta subunit 1
  $1,657.00
4 Weeks*

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Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol SCN1B
Locus ID 6324
Components

GA104291G1, SCN1B gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA104291G2, SCN1B gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA104291G3, SCN1B gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001037, NM_199037, NM_001321605
UniProt ID Q07699
Synonyms ATFB13; BRGDA5; GEFSP1
Summary Voltage-gated sodium channels are heteromeric proteins that function in the generation and propagation of action potentials in muscle and neuronal cells. They are composed of one alpha and two beta subunits, where the alpha subunit provides channel activity and the beta-1 subunit modulates the kinetics of channel inactivation. This gene encodes a sodium channel beta-1 subunit. Mutations in this gene result in generalized epilepsy with febrile seizures plus, Brugada syndrome 5, and defects in cardiac conduction. Multiple transcript variants encoding different isoforms have been found for this gene.provided by RefSeq, Oct 2009
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Documents
Resources
Other Versions
SKU Description Size Price
KN409565 SCN1B - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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