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Human RPL5 activation kit by CRISPRa

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SKU
GA104146
RPL5 CRISPRa kit - CRISPR gene activation of human ribosomal protein L5
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA335157 Rabbit polyclonal Anti-RPL5 Antibody
100 ul
$585.00
RC210734 RPL5 (Myc-DDK-tagged)-Human ribosomal protein L5 (RPL5)
10 ug
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Other products for "RPL5"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol RPL5
Locus ID 6125
Components

GA104146G1, RPL5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA104146G2, RPL5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA104146G3, RPL5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_000969, NR_146333
UniProt ID P46777
Synonyms DBA6; L5; MSTP030; PPP1R135
Summary Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of four RNA species and approximately 80 structurally distinct proteins. This gene encodes a member of the L18P family of ribosomal proteins and component of the 60S subunit. The encoded protein binds 5S rRNA to form a stable complex called the 5S ribonucleoprotein particle (RNP), which is necessary for the transport of nonribosome-associated cytoplasmic 5S rRNA to the nucleolus for assembly into ribosomes. The encoded protein may also function to inhibit tumorigenesis through the activation of downstream tumor suppressors and the downregulation of oncoprotein expression. Mutations in this gene have been identified in patients with Diamond-Blackfan Anemia (DBA). This gene is co-transcribed with the small nucleolar RNA gene U21, which is located in its fifth intron. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed throughout the genome. provided by RefSeq, Mar 2017
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Documents
Resources
Other Versions
SKU Description Size Price
KN410734 RPL5 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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