Human ROBO2 activation kit by CRISPRa

SKU GA104127

ROBO2 CRISPRa kit - CRISPR gene activation of human roundabout guidance receptor 2

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: ROBO2
• Locus ID: 6092
• Components:

  GA104127G1, ROBO2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104127G2, ROBO2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104127G3, ROBO2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001128929, NM_001290039, NM_001290040, NM_001290065, NM_002942
• UniProt ID: Q9HCK4
• Synonyms: SAX3
• Summary: The protein encoded by this gene belongs to the ROBO family, part of the immunoglobulin superfamily of proteins that are highly conserved from fly to human. The encoded protein is a transmembrane receptor for the slit homolog 2 protein and functions in axon guidance and cell migration. Mutations in this gene are associated with vesicoureteral reflux, characterized by the backward flow of urine from the bladder into the ureters or the kidney. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]