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Human RGR activation kit by CRISPRa

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SKU
GA104089
RGR CRISPRa kit - CRISPR gene activation of human retinal G protein coupled receptor
  $1,657.00
4 Weeks*

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RC203778L1V Lenti ORF particles, RGR (Myc-DDK tagged) - Human retinal G protein coupled receptor (RGR), transcript variant 1, 200ul, >10^7 TU/mL
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Other products for "RGR"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol RGR
Locus ID 5995
Components

GA104089G1, RGR gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA104089G2, RGR gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA104089G3, RGR gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001012720, NM_001012722, NM_002921
UniProt ID P47804
Synonyms RP44
Summary This gene encodes a putative retinal G-protein coupled receptor. The gene is a member of the opsin subfamily of the 7 transmembrane, G-protein coupled receptor 1 family. Like other opsins which bind retinaldehyde, it contains a conserved lysine residue in the seventh transmembrane domain. The protein acts as a photoisomerase to catalyze the conversion of all-trans-retinal to 11-cis-retinal. The reverse isomerization occurs with rhodopsin in retinal photoreceptor cells. The protein is exclusively expressed in tissue adjacent to retinal photoreceptor cells, the retinal pigment epithelium and Mueller cells. This gene may be associated with autosomal recessive and autosomal dominant retinitis pigmentosa (arRP and adRP, respectively). Alternative splicing results in multiple transcript variants encoding different isoforms. provided by RefSeq, Jul 2008
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Documents
Resources
Other Versions
SKU Description Size Price
KN403778 RGR - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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