Human REV3L activation kit by CRISPRa

SKU GA104074

REV3L CRISPRa kit - CRISPR gene activation of human REV3 like, DNA directed polymerase zeta catalytic subunit

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: REV3L
• Locus ID: 5980
• Components:

  GA104074G1, REV3L gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104074G2, REV3L gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104074G3, REV3L gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001286431, NM_001286432, NM_002912
• UniProt ID: O60673
• Synonyms: POLZ; REV3
• Summary: The protein encoded by this gene represents the catalytic subunit of DNA polymerase zeta, which functions in translesion DNA synthesis. The encoded protein can be found in mitochondria, where it protects DNA from damage. Defects in this gene are a cause of Mobius syndrome. [provided by RefSeq, Jan 2017]