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Human UPF1 activation kit by CRISPRa

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SKU
GA104070
UPF1 CRISPRa kit - CRISPR gene activation of human UPF1 RNA helicase and ATPase
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA350889 Rabbit Polyclonal Anti-UPF1 Antibody
100 ul
$205.00
RC208018 UPF1 (Myc-DDK-tagged)-Human UPF1 regulator of nonsense transcripts homolog (yeast) (UPF1)
10 ug
$1,459.00

Other products for "UPF1"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol UPF1
Locus ID 5976
Components

GA104070G1, UPF1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA104070G2, UPF1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA104070G3, UPF1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001297549, NM_002911
UniProt ID Q92900
Synonyms HUPF1; NORF1; pNORF1; RENT1; smg-2
Summary This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located only in the cytoplasm. When translation ends, it interacts with the protein that is a functional homolog of yeast Upf2p to trigger mRNA decapping. Use of multiple polyadenylation sites has been noted for this gene. Alternative splicing results in multiple transcript variants. provided by RefSeq, Jul 2014
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Other Versions
SKU Description Size Price
KN408018 UPF1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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