Human RAP2B activation kit by CRISPRa

SKU GA104022

RAP2B CRISPRa kit - CRISPR gene activation of human RAP2B, member of RAS oncogene family

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: RAP2B
• Locus ID: 5912
• Components:

  GA104022G1, RAP2B gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104022G2, RAP2B gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104022G3, RAP2B gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_002886
• UniProt ID: P61225
• Synonyms: MGC20484
• Summary: This intronless gene belongs to a family of RAS-related genes. The proteins encoded by these genes share approximately 50% amino acid identity with the classical RAS proteins and have numerous structural features in common. The most striking difference between the RAP and RAS proteins resides in their 61st amino acid: glutamine in RAS is replaced by threonine in RAP proteins. Evidence suggests that this protein may be polyisoprenylated and palmitoylated. [provided by RefSeq, Jul 2008]