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Human RANBP2 activation kit by CRISPRa

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SKU
GA104015
RANBP2 CRISPRa kit - CRISPR gene activation of human RAN binding protein 2
  $1,657.00
4 Weeks*

Other products for "RANBP2"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol RANBP2
Locus ID 5903
Components

GA104015G1, RANBP2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA104015G2, RANBP2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA104015G3, RANBP2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_006267
UniProt ID P49792
Synonyms ADANE; ANE1; IIAE3; NUP358; TRP1; TRP2
Summary RAN is a small GTP-binding protein of the RAS superfamily that is associated with the nuclear membrane and is thought to control a variety of cellular functions through its interactions with other proteins. This gene encodes a very large RAN-binding protein that immunolocalizes to the nuclear pore complex. The protein is a giant scaffold and mosaic cyclophilin-related nucleoporin implicated in the Ran-GTPase cycle. The encoded protein directly interacts with the E2 enzyme UBC9 and strongly enhances SUMO1 transfer from UBC9 to the SUMO1 target SP100. These findings place sumoylation at the cytoplasmic filaments of the nuclear pore complex and suggest that, for some substrates, modification and nuclear import are linked events. This gene is partially duplicated in a gene cluster that lies in a hot spot for recombination on chromosome 2q. provided by RefSeq, Jul 2008
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Documents
Resources
Other Versions
SKU Description Size Price
KN416162 RANBP2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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