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Human PEX5 activation kit by CRISPRa

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SKU
GA103965
PEX5 CRISPRa kit - CRISPR gene activation of human peroxisomal biogenesis factor 5
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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Other products for "PEX5"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol PEX5
Locus ID 5830
Components

GA103965G1, PEX5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA103965G2, PEX5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA103965G3, PEX5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_000319, NM_001131023, NM_001131024, NM_001131025, NM_001131026, NM_001300789, NM_001351124, NM_001351126, NM_001351127, NM_001351128, NM_001351130, NM_001351131, NM_001351132, NM_001351133, NM_001351134, NM_001351135, NM_001351136, NM_001351137, NM_001351138, NM_001351139, NM_001351140
UniProt ID P50542
Synonyms PBD2A; PBD2B; PTS1-BP; PTS1R; PXR1; RCDP5
Summary The product of this gene binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import. Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. The peroxisomal biogenesis disorders are a heterogeneous group with at least 14 complementation groups and with more than 1 phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of neonatal adrenoleukodystrophy (NALD), a cause of Zellweger syndrome (ZWS) as well as may be a cause of infantile Refsum disease (IRD). Alternatively spliced transcript variants encoding different isoforms have been identified. provided by RefSeq, Oct 2008
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Documents
Resources
Other Versions
SKU Description Size Price
KN402062 PEX5 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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