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Human PTPRN2 activation kit by CRISPRa

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SKU
GA103943
PTPRN2 CRISPRa kit - CRISPR gene activation of human protein tyrosine phosphatase receptor type N2
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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100 ul
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RC213126 PTPRN2 (Myc-DDK-tagged)-Human protein tyrosine phosphatase, receptor type, N polypeptide 2 (PTPRN2), transcript variant 2
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Other products for "PTPRN2"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol PTPRN2
Locus ID 5799
Components

GA103943G1, PTPRN2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA103943G2, PTPRN2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA103943G3, PTPRN2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001308267, NM_001308268, NM_002847, NM_130842, NM_130843
UniProt ID Q92932
Synonyms IA-2beta; IAR; ICAAR; PTPRP; R-PTP-N2
Summary This gene encodes a protein with sequence similarity to receptor-like protein tyrosine phosphatases. However, tyrosine phosphatase activity has not been experimentally validated for this protein. Studies of the rat ortholog suggest that the encoded protein may instead function as a phosphatidylinositol phosphatase with the ability to dephosphorylate phosphatidylinositol 3-phosphate and phosphatidylinositol 4,5-diphosphate, and this function may be involved in the regulation of insulin secretion. This protein has been identified as an autoantigen in insulin-dependent diabetes mellitus. Alternative splicing results in multiple transcript variants. provided by RefSeq, Feb 2015
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Documents
Resources
Other Versions
SKU Description Size Price
KN405368 PTPRN2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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