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Human LAR (PTPRF) activation kit by CRISPRa

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SKU
GA103936
PTPRF CRISPRa kit - CRISPR gene activation of human protein tyrosine phosphatase receptor type F
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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RC224381 PTPRF (Myc-DDK-tagged)-Human protein tyrosine phosphatase, receptor type, F (PTPRF), transcript variant 1
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Other products for "PTPRF"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol PTPRF
Locus ID 5792
Components

GA103936G1, LAR gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA103936G2, LAR gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA103936G3, LAR gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_002840, NM_130440, NM_001329137, NM_001329138, NM_001329139, NM_001329140
UniProt ID P10586
Synonyms BNAH2; LAR
Summary The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains three Ig-like domains, and nine non-Ig like domains similar to that of neural-cell adhesion molecule. This PTP was shown to function in the regulation of epithelial cell-cell contacts at adherents junctions, as well as in the control of beta-catenin signaling. An increased expression level of this protein was found in the insulin-responsive tissue of obese, insulin-resistant individuals, and may contribute to the pathogenesis of insulin resistance. Two alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported. provided by RefSeq, Jul 2008
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Documents
Resources
Other Versions
SKU Description Size Price
KN207873 PTPRF - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN207873BN PTPRF - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN207873LP PTPRF - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN207873RB PTPRF - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN407873 PTPRF - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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