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Human PKN1 activation kit by CRISPRa

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SKU
GA103775
PKN1 CRISPRa kit - CRISPR gene activation of human protein kinase N1
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA313071 Rabbit polyclonal anti-PKN1/PRK1 antibody
100 ul
$380.00
RC207788 PKN1 (Myc-DDK-tagged)-Human protein kinase N1 (PKN1), transcript variant 2
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Other products for "PKN1"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol PKN1
Locus ID 5585
Components

GA103775G1, PKN1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA103775G2, PKN1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA103775G3, PKN1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_002741, NM_213560
UniProt ID Q16512
Synonyms DBK; PAK-1; PAK1; PKN; PKN-ALPHA; PRK1; PRKCL1
Summary The protein encoded by this gene belongs to the protein kinase C superfamily. This kinase is activated by Rho family of small G proteins and may mediate the Rho-dependent signaling pathway. This kinase can be activated by phospholipids and by limited proteolysis. The 3-phosphoinositide dependent protein kinase-1 (PDPK1/PDK1) is reported to phosphorylate this kinase, which may mediate insulin signals to the actin cytoskeleton. The proteolytic activation of this kinase by caspase-3 or related proteases during apoptosis suggests its role in signal transduction related to apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed. provided by RefSeq, Jul 2008
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Documents
Resources
Other Versions
SKU Description Size Price
KN407788 PKN1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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