Human PRB1 activation kit by CRISPRa

SKU GA103740

PRB1 CRISPRa kit - CRISPR gene activation of human proline rich protein BstNI subfamily 1 (gene/pseudogene)

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: PRB1
• Locus ID: 5542
• Components:

  GA103740G1, PRB1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103740G2, PRB1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103740G3, PRB1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_005039, NM_199353, NM_199354, NR_160307
• UniProt ID: P04280
• Synonyms: PM; PMF; PMS; PRB1L; PRB1M
• Summary: This gene encodes a member of the heterogeneous family of basic, proline-rich, human salivary glycoproteins. The encoded preproprotein undergoes proteolytic processing to generate one or more mature peptides before secretion from the parotid glands. Multiple alleles of this gene exhibiting variations in the length of the tandem repeats have been identified. The reference genome encodes the "Medium" allele. This gene is located in a cluster of closely related salivary proline-rich proteins on chromosome 12. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing. [provided by RefSeq, Nov 2015]