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Human Oct4 (POU5F1) activation kit by CRISPRa

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SKU
GA103682
POU5F1 CRISPRa kit - CRISPR gene activation of human POU class 5 homeobox 1
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA500035 OCT4 mouse monoclonal antibody, clone OTI9B7 (formerly 9B7) 100 ul
$447.00
RC211998 POU5F1/OCT4 (Myc-DDK-tagged)-Human POU class 5 homeobox 1 (POU5F1/OCT4), transcript variant 1
10 ug
$457.00

Other products for "POU5F1"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol POU5F1
Locus ID 5460
Components

GA103682G1, Oct4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA103682G2, Oct4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA103682G3, Oct4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001173531, NM_001285986, NM_001285987, NM_002701, NM_203289
UniProt ID Q01860
Synonyms Oct-3; Oct-4; OCT3; OCT4; OTF-3; OTF3; OTF4
Summary This gene encodes a transcription factor containing a POU homeodomain that plays a key role in embryonic development and stem cell pluripotency. Aberrant expression of this gene in adult tissues is associated with tumorigenesis. This gene can participate in a translocation with the Ewing's sarcoma gene on chromosome 21, which also leads to tumor formation. Alternative splicing, as well as usage of alternative AUG and non-AUG translation initiation codons, results in multiple isoforms. One of the AUG start codons is polymorphic in human populations. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12. provided by RefSeq, Oct 2013
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Documents
Resources
Other Versions
SKU Description Size Price
KN411998 POU5F1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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