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Human PON1 activation kit by CRISPRa

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SKU
GA103667
PON1 CRISPRa kit - CRISPR gene activation of human paraoxonase 1
  $1,657.00
4 Weeks*

Frequently Bought Together (1)

RC210356 PON1 (Myc-DDK-tagged)-Human paraoxonase 1 (PON1)
10 ug
$457.00

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Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol PON1
Locus ID 5444
Components

GA103667G1, PON1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA103667G2, PON1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA103667G3, PON1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_000446
UniProt ID P27169
Synonyms ESA; MVCD5; PON
Summary This gene encodes a member of the paraoxonase family of enzymes and exhibits lactonase and ester hydrolase activity. Following synthesis in the kidney and liver, the enzyme is secreted into the circulation, where it binds to high density lipoprotein (HDL) particles and hydrolyzes thiolactones and xenobiotics, including paraoxon, a metabolite of the insecticide parathion. Polymorphisms in this gene may be associated with coronary artery disease and diabetic retinopathy. The gene is found in a cluster of three related paraoxonase genes on chromosome 7. provided by RefSeq, Aug 2017
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Documents
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Other Versions
SKU Description Size Price
KN410356 PON1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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