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Human POLR2E activation kit by CRISPRa

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SKU
GA103657
POLR2E CRISPRa kit - CRISPR gene activation of human RNA polymerase II subunit E
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA502548 POLR2E mouse monoclonal antibody, clone OTI3B5 (formerly 3B5) 100 ul
$447.00
RC201266 POLR2E (Myc-DDK-tagged)-Human polymerase (RNA) II (DNA directed) polypeptide E, 25kDa (POLR2E)
10 ug
$300.00

Other products for "POLR2E"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol POLR2E
Locus ID 5434
Components

GA103657G1, POLR2E gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA103657G2, POLR2E gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA103657G3, POLR2E gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001316323, NM_001316324, NM_002695
UniProt ID P19388
Synonyms hRPB25; hsRPB5; RPABC1; RPB5; XAP4
Summary This gene encodes the fifth largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This subunit is shared by the other two DNA-directed RNA polymerases and is present in two-fold molar excess over the other polymerase subunits. An interaction between this subunit and a hepatitis virus transactivating protein has been demonstrated, suggesting that interaction between transcriptional activators and the polymerase can occur through this subunit. A pseudogene is located on chromosome 11. Three transcript variants encoding two different isoforms have been found for this gene. provided by RefSeq, Oct 2015
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Documents
Resources
Other Versions
SKU Description Size Price
KN401266 POLR2E - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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