Human MCH (PMCH) activation kit by CRISPRa

SKU GA103624

PMCH CRISPRa kit - CRISPR gene activation of human pro-melanin concentrating hormone

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: PMCH
• Locus ID: 5367
• Components:

  GA103624G1, MCH gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103624G2, MCH gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103624G3, MCH gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_002674
• UniProt ID: P20382
• Synonyms: MCH; ppMCH
• Summary: This gene encodes a preproprotein that is proteolytically processed to generate multiple protein products. These products include melanin-concentrating hormone (MCH), neuropeptide-glutamic acid-isoleucine (NEI), and neuropeptide-glycine-glutamic acid (NGE). Melanin-concentrating hormone is a 19-amino acid neuropeptide that stimulates hunger and may additionally regulate energy homeostasis, reproductive function, and sleep. Pseudogenes of this gene have been identified on chromosome 5. [provided by RefSeq, Jul 2015]