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Human PLOD2 activation kit by CRISPRa

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SKU
GA103611
PLOD2 CRISPRa kit - CRISPR gene activation of human procollagen-lysine,2-oxoglutarate 5-dioxygenase 2
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA803224 PLOD2 mouse monoclonal antibody, clone OTI6D1 (formerly 6D1) 100 ul
$447.00
RC207610 PLOD2 (Myc-DDK-tagged)-Human procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 (PLOD2), transcript variant 1
10 ug
$1,041.00

Other products for "PLOD2"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol PLOD2
Locus ID 5352
Components

GA103611G1, PLOD2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA103611G2, PLOD2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA103611G3, PLOD2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_000935, NM_182943
UniProt ID O00469
Synonyms BRKS2; LH2; TLH
Summary The protein encoded by this gene is a membrane-bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VIB have deficiencies in lysyl hydroxylase activity. Mutations in the coding region of this gene are associated with Bruck syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms. provided by RefSeq, Jul 2008
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Documents
Resources
Other Versions
SKU Description Size Price
KN407610 PLOD2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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