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Human PIK3C2B activation kit by CRISPRa

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SKU
GA103552
PIK3C2B CRISPRa kit - CRISPR gene activation of human phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA506011 PIK3C2B mouse monoclonal antibody, clone OTI2G3 (formerly 2G3) 100 ul
$447.00
RC218354 PIK3C2B (Myc-DDK-tagged)-Human phosphoinositide-3-kinase, class 2, beta polypeptide (PIK3C2B)
10 ug
$2,096.00

Other products for "PIK3C2B"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol PIK3C2B
Locus ID 5287
Components

GA103552G1, PIK3C2B gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA103552G2, PIK3C2B gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA103552G3, PIK3C2B gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_002646
UniProt ID O00750
Synonyms C2-PI3K
Summary The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. The PI3-kinase activity of this protein is sensitive to low nanomolar levels of the inhibitor wortmanin. The C2 domain of this protein was shown to bind phospholipids but not Ca2+, which suggests that this enzyme may function in a calcium-independent manner. provided by RefSeq, Jul 2008
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Documents
Resources
Other Versions
SKU Description Size Price
KN418354 PIK3C2B - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

file-alt Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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