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Human SERPINB6 activation kit by CRISPRa

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SKU
GA103538
SERPINB6 CRISPRa kit - CRISPR gene activation of human serpin family B member 6
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol SERPINB6
Locus ID 5269
Components

GA103538G1, SERPINB6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA103538G2, SERPINB6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA103538G3, SERPINB6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001195291, NM_001271822, NM_001271823, NM_001271824, NM_001271825, NM_001297699, NM_001297700, NM_004568
UniProt ID P35237
Synonyms CAP; DFNB91; MSTP057; PI-6; PI6; PTI; SPI3
Summary The protein encoded by this gene is a member of the serpin (serine proteinase inhibitor) superfamily, and ovalbumin(ov)-serpin subfamily. It was originally discovered as a placental thrombin inhibitor. The mouse homolog was found to be expressed in the hair cells of the inner ear. Mutations in this gene are associated with nonsyndromic progressive hearing loss, suggesting that this serpin plays an important role in the inner ear in the protection against leakage of lysosomal content during stress, and that loss of this protection results in cell death and sensorineural hearing loss. Alternatively spliced transcript variants have been found for this gene. provided by RefSeq, Sep 2010
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Documents
Resources
Other Versions
SKU Description Size Price
KN400668 SERPINB6 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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