Human PGK2 activation kit by CRISPRa

SKU GA103516

PGK2 CRISPRa kit - CRISPR gene activation of human phosphoglycerate kinase 2

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: PGK2
• Locus ID: 5232
• Components:

  GA103516G1, PGK2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103516G2, PGK2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103516G3, PGK2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_138733
• UniProt ID: P07205
• Synonyms: dJ417L20.2; HEL-S-272; PGKB; PGKPS
• Summary: This gene is intronless, arose via retrotransposition of the phosphoglycerate kinase 1 gene, and is expressed specifically in the testis. Initially assumed to be a pseudogene, the encoded protein is actually a functional phosphoglycerate kinase that catalyzes the reversible conversion of 1,3-bisphosphoglycerate to 3-phosphoglycerate, during the Embden-Meyerhof-Parnas pathway of glycolysis, in the later stages of spermatogenesis.[provided by RefSeq, May 2010]