Human PFKFB2 activation kit by CRISPRa

SKU
GA103498
PFKFB2 CRISPRa kit - CRISPR gene activation of human 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol PFKFB2
Locus ID 5208
Components

GA103498G1, PFKFB2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA103498G2, PFKFB2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA103498G3, PFKFB2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001018053, NM_006212
UniProt ID O60825
Synonyms PFK-2/FBPase-2
Summary The protein encoded by this gene is involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate, and a fructose-2,6-biphosphatase activity that catalyzes the degradation of fructose-2,6-bisphosphate. This protein regulates fructose-2,6-bisphosphate levels in the heart, while a related enzyme encoded by a different gene regulates fructose-2,6-bisphosphate levels in the liver and muscle. This enzyme functions as a homodimer. Two transcript variants encoding two different isoforms have been found for this gene. provided by RefSeq, Jul 2008
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Documents
Resources
Other Versions
SKU Description Size Price
KN211329 PFKFB2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN211329BN PFKFB2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN211329LP PFKFB2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN211329RB PFKFB2 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN411329 PFKFB2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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