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Human PFKFB1 activation kit by CRISPRa

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SKU
GA103497
PFKFB1 CRISPRa kit - CRISPR gene activation of human 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA350927 Rabbit Polyclonal Anti-PFKFB1 Antibody
100 ul
$205.00
RC224599 PFKFB1 (Myc-DDK-tagged)-Human 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 (PFKFB1)
10 ug
$457.00

Other products for "PFKFB1"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol PFKFB1
Locus ID 5207
Components

GA103497G1, PFKFB1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA103497G2, PFKFB1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA103497G3, PFKFB1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001271804, NM_001271805, NM_002625, NR_073450
UniProt ID P16118
Synonyms F6PK; HL2K; PFRX
Summary This gene encodes a member of the family of bifunctional 6-phosphofructo-2-kinase:fructose-2,6-biphosphatase enzymes. The enzyme forms a homodimer that catalyzes both the synthesis and degradation of fructose-2,6-biphosphate using independent catalytic domains. Fructose-2,6-biphosphate is an activator of the glycolysis pathway and an inhibitor of the gluconeogenesis pathway. Consequently, regulating fructose-2,6-biphosphate levels through the activity of this enzyme is thought to regulate glucose homeostasis. Multiple alternatively spliced transcript variants have been found for this gene. provided by RefSeq, Nov 2012
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Documents
Resources
Other Versions
SKU Description Size Price
KN424599 PFKFB1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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