Human PEPD activation kit by CRISPRa

SKU GA103477

PEPD CRISPRa kit - CRISPR gene activation of human peptidase D

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: PEPD
• Locus ID: 5184
• Components:

  GA103477G1, PEPD gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103477G2, PEPD gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103477G3, PEPD gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_000285, NM_001166056, NM_001166057, NM_032652
• UniProt ID: P12955
• Synonyms: PROLIDASE
• Summary: This gene encodes a member of the peptidase family. The protein forms a homodimer that hydrolyzes dipeptides or tripeptides with C-terminal proline or hydroxyproline residues. The enzyme serves an important role in the recycling of proline, and may be rate limiting for the production of collagen. Mutations in this gene result in prolidase deficiency, which is characterized by the excretion of large amount of di- and tri-peptides containing proline. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009]