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Human PDHB activation kit by CRISPRa

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SKU
GA103459
PDHB CRISPRa kit - CRISPR gene activation of human pyruvate dehydrogenase E1 beta subunit
  $1,657.00
4 Weeks*

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Other products for "PDHB"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol PDHB
Locus ID 5162
Components

GA103459G1, PDHB gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA103459G2, PDHB gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA103459G3, PDHB gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_000925, NM_001173468, NM_001315536, NR_033384
UniProt ID P11177
Synonyms PDHBD; PDHE1-B; PHE1B
Summary The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and carbon dioxide, and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 beta subunit. Mutations in this gene are associated with pyruvate dehydrogenase E1-beta deficiency. Alternatively spliced transcript variants have been found for this gene. provided by RefSeq, Mar 2012
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Other Versions
SKU Description Size Price
KN401230 PDHB - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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