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Human PDGF Receptor beta (PDGFRB) activation kit by CRISPRa

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SKU
GA103456
PDGFRB CRISPRa kit - CRISPR gene activation of human platelet derived growth factor receptor beta
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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Other products for "PDGFRB"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol PDGFRB
Locus ID 5159
Components

GA103456G1, PDGF Receptor beta gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA103456G2, PDGF Receptor beta gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA103456G3, PDGF Receptor beta gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_002609, NM_001355016, NM_001355017, NR_149150
UniProt ID P09619
Synonyms CD140B; IBGC4; IMF1; JTK12; PDGFR; PDGFR-1; PDGFR1
Summary The protein encoded by this gene is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer (PDGFB or PDGFD) or a heterodimer (PDGFA and PDGFB). This gene is essential for normal development of the cardiovascular system and aids in rearrangement of the actin cytoskeleton. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the ETV6 gene, results in chronic myeloproliferative disorder with eosinophilia. provided by RefSeq, Aug 2017
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Documents
Resources
Other Versions
SKU Description Size Price
KN406377 PDGFRB - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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