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Human PDE6 beta (PDE6B) activation kit by CRISPRa

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SKU
GA103455
PDE6B CRISPRa kit - CRISPR gene activation of human phosphodiesterase 6B
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA379736 PDE6B Rabbit polyclonal Antibody
100 ul
$410.00
RC200445 PDE6B (Myc-DDK-tagged)-Human phosphodiesterase 6B, cGMP-specific, rod, beta (PDE6B), transcript variant 1
10 ug
$781.00

Other products for "PDE6B"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol PDE6B
Locus ID 5158
Components

GA103455G1, PDE6 beta gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA103455G2, PDE6 beta gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA103455G3, PDE6 beta gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_000283, NM_001145291, NM_001145292, NM_001350154, NM_001350155
UniProt ID P35913
Synonyms CSNB3; CSNBAD2; PDEB; rd1; RP40
Summary Photon absorption triggers a signaling cascade in rod photoreceptors that activates cGMP phosphodiesterase (PDE), resulting in the rapid hydrolysis of cGMP, closure of cGMP-gated cation channels, and hyperpolarization of the cell. PDE is a peripheral membrane heterotrimeric enzyme made up of alpha, beta, and gamma subunits. This gene encodes the beta subunit. Mutations in this gene result in retinitis pigmentosa and autosomal dominant congenital stationary night blindness. Multiple transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Feb 2009
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Documents
Resources
Other Versions
SKU Description Size Price
KN400445 PDE6B - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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