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Human PDE6 alpha (PDE6A) activation kit by CRISPRa

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SKU
GA103442
PDE6A CRISPRa kit - CRISPR gene activation of human phosphodiesterase 6A
  $1,657.00
4 Weeks*

Frequently Bought Together (1)

RC207783 PDE6A (Myc-DDK-tagged)-Human phosphodiesterase 6A, cGMP-specific, rod, alpha (PDE6A)
10 ug
$787.00

Other products for "PDE6A"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol PDE6A
Locus ID 5145
Components

GA103442G1, PDE6 alpha gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA103442G2, PDE6 alpha gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA103442G3, PDE6 alpha gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_000440
UniProt ID P16499
Synonyms CGPR-A; PDEA; RP43
Summary This gene encodes the cyclic-GMP (cGMP)-specific phosphodiesterase 6A alpha subunit, expressed in cells of the retinal rod outer segment. The phosphodiesterase 6 holoenzyme is a heterotrimer composed of an alpha, beta, and two gamma subunits. cGMP is an important regulator of rod cell membrane current, and its dynamic concentration is established by phosphodiesterase 6A cGMP hydrolysis and guanylate cyclase cGMP synthesis. The protein is a subunit of a key phototransduction enzyme and participates in processes of transmission and amplification of the visual signal. Mutations in this gene have been identified as one cause of autosomal recessive retinitis pigmentosa. provided by RefSeq, Jul 2008
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Documents
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Other Versions
SKU Description Size Price
KN407783 PDE6A - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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