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Human PDE1A activation kit by CRISPRa

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SKU
GA103433
PDE1A CRISPRa kit - CRISPR gene activation of human phosphodiesterase 1A
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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RC205292 PDE1A (Myc-DDK-tagged)-Human phosphodiesterase 1A, calmodulin-dependent (PDE1A), transcript variant 1
10 ug
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Other products for "PDE1A"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol PDE1A
Locus ID 5136
Components

GA103433G1, PDE1A gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA103433G2, PDE1A gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA103433G3, PDE1A gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001003683, NM_001258312, NM_001258313, NM_001258314, NM_005019, NM_001363871
UniProt ID P54750
Synonyms CAM-PDE-1A; HCAM-1; HCAM1; HSPDE1A
Summary Cyclic nucleotide phosphodiesterases (PDEs) play a role in signal transduction by regulating intracellular cyclic nucleotide concentrations through hydrolysis of cAMP and/or cGMP to their respective nucleoside 5-prime monophosphates. Members of the PDE1 family, such as PDE1A, are Ca(2+)/calmodulin (see CALM1; MIM 114180)-dependent PDEs (CaM-PDEs) that are activated by calmodulin in the presence of Ca(2+) (Michibata et al., 2001 PubMed 11342109; Fidock et al., 2002 PubMed 11747989).supplied by OMIM, Oct 2009
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Documents
Resources
Other Versions
SKU Description Size Price
KN405292 PDE1A - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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