Human PCM1 activation kit by CRISPRa

SKU
GA103416
PCM1 CRISPRa kit - CRISPR gene activation of human pericentriolar material 1
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol PCM1
Locus ID 5108
Components

GA103416G1, PCM1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA103416G2, PCM1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA103416G3, PCM1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001315507, NM_001315508, NM_006197, NM_001352632, NM_001352633, NM_001352634, NM_001352635, NM_001352636, NM_001352637, NM_001352638, NM_001352639, NM_001352640, NM_001352641, NM_001352642, NM_001352643, NM_001352644, NM_001352645, NM_001352646, NM_001352647, NM_001352648, NM_001352649, NM_001352650, NM_001352651, NM_001352652, NM_001352653, NM_001352654, NM_001352655, NM_001352656, NM_001352657, NM_001352658, NM_001352659, NM_001352660, NR_148032
UniProt ID Q15154
Synonyms PTC4
Summary The protein encoded by this gene is a component of centriolar satellites, which are electron dense granules scattered around centrosomes. Inhibition studies show that this protein is essential for the correct localization of several centrosomal proteins, and for anchoring microtubules to the centrosome. Chromosomal aberrations involving this gene are associated with papillary thyroid carcinomas and a variety of hematological malignancies, including atypical chronic myeloid leukemia and T-cell lymphoma. Multiple transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Oct 2015
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Documents
Resources
Other Versions
SKU Description Size Price
KN415826 PCM1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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