Human PCCA activation kit by CRISPRa

SKU
GA103406
PCCA CRISPRa kit - CRISPR gene activation of human propionyl-CoA carboxylase subunit alpha
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol PCCA
Locus ID 5095
Components

GA103406G1, PCCA gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA103406G2, PCCA gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA103406G3, PCCA gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_000282, NM_001127692, NM_001178004, NM_001352605, NM_001352606, NM_001352607, NM_001352608, NM_001352609, NM_001352610, NM_001352611, NM_001352612, NR_148027, NR_148028, NR_148029, NR_148030, NR_148031
UniProt ID P05165
Synonyms PCCase alpha subunit; propanoyl-CoA:carbon dioxide ligase alpha subunit; propionyl-CoA carboxylase alpha chain, mitochondrial; propionyl-coenzyme A carboxylase, alpha polypeptide; Propionyl Coenzyme A carboxylase alpha polypeptide
Summary The protein encoded by this gene is the alpha subunit of the heterodimeric mitochondrial enzyme Propionyl-CoA carboxylase. PCCA encodes the biotin-binding region of this enzyme. Mutations in either PCCA or PCCB (encoding the beta subunit) lead to an enzyme deficiency resulting in propionic acidemia. Multiple transcript variants encoding different isoforms have been found for this gene.provided by RefSeq, May 2010
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Documents
Resources
Other Versions
SKU Description Size Price
KN414832 PCCA - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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