Human PAK3 activation kit by CRISPRa

SKU
GA103380
PAK3 CRISPRa kit - CRISPR gene activation of human p21 (RAC1) activated kinase 3
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol PAK3
Locus ID 5063
Components

GA103380G1, PAK3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA103380G2, PAK3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA103380G3, PAK3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001128166, NM_001128167, NM_001128168, NM_001128172, NM_001128173, NM_001324325, NM_001324326, NM_001324327, NM_001324328, NM_001324329, NM_001324330, NM_001324331, NM_001324332, NM_001324333, NM_001324334, NM_002578, NR_136740, NR_136741, NR_136742, NR_136743, NR_136744, NR_136745, NR_136746, NR_136747, NR_136748
UniProt ID O75914
Synonyms ARA; beta-PAK; bPAK; MRX30; MRX47; OPHN3; PAK-3; PAK3beta
Summary The protein encoded by this gene is a serine-threonine kinase and forms an activated complex with GTP-bound RAS-like (P21), CDC2 and RAC1. This protein may be necessary for dendritic development and for the rapid cytoskeletal reorganization in dendritic spines associated with synaptic plasticity. Defects in this gene are the cause of a non-syndromic form of X-linked intellectual disability. Alternatively spliced transcript variants encoding different isoforms have been identified. provided by RefSeq, Jul 2017
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Documents
Resources
Other Versions
SKU Description Size Price
KN422595 PAK3 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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