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Human OAS1 activation kit by CRISPRa

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SKU
GA103298
OAS1 CRISPRa kit - CRISPR gene activation of human 2'-5'-oligoadenylate synthetase 1
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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100 ul
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RC200696 OAS1 (Myc-DDK-tagged)-Human 2',5'-oligoadenylate synthetase 1, 40/46kDa (OAS1), transcript variant 2
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Other products for "OAS1"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol OAS1
Locus ID 4938
Components

GA103298G1, OAS1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA103298G2, OAS1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA103298G3, OAS1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001032409, NM_001320151, NM_002534, NM_016816
UniProt ID P00973
Synonyms IFI-4; OIAS; OIASI
Summary This gene is induced by interferons and encodes a protein that synthesizes 2',5'-oligoadenylates (2-5As). This protein activates latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. Alternative splicing results in multiple transcript variants with different enzymatic activities. Polymorphisms in this gene have been associated with susceptibility to viral infection and diabetes mellitus, type 1. A disease-associated allele in a splice acceptor site influences the production of the p46 splice isoform. This gene is located in a cluster of related genes on chromosome 12. provided by RefSeq, Feb 2016
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Documents
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Other Versions
SKU Description Size Price
KN400696 OAS1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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