Human CD73 (NT5E) activation kit by CRISPRa

SKU GA103277

NT5E CRISPRa kit - CRISPR gene activation of human 5'-nucleotidase ecto

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: NT5E
• Locus ID: 4907
• Components:

  GA103277G1, CD73 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103277G2, CD73 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103277G3, CD73 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001204813, NM_002526
• UniProt ID: P21589
• Synonyms: CALJA; CD73; E5NT; eN; eNT; NT; NT5; NTE
• Summary: The protein encoded by this gene is a plasma membrane protein that catalyzes the conversion of extracellular nucleotides to membrane-permeable nucleosides. The encoded protein is used as a determinant of lymphocyte differentiation. Defects in this gene can lead to the calcification of joints and arteries. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2011]