Human NRL activation kit by CRISPRa

SKU GA103273

NRL CRISPRa kit - CRISPR gene activation of human neural retina leucine zipper

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: NRL
• Locus ID: 4901
• Components:

  GA103273G1, NRL gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103273G2, NRL gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103273G3, NRL gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_006177, NM_001354768, NM_001354769, NM_001354770
• UniProt ID: P54845
• Synonyms: D14S46E; NRL-MAF; RP27
• Summary: This gene encodes a basic motif-leucine zipper transcription factor of the Maf subfamily. The encoded protein is conserved among vertebrates and is a critical intrinsic regulator of photoceptor development and function. Mutations in this gene have been associated with retinitis pigmentosa and retinal degenerative diseases. [provided by RefSeq, Jul 2008]