Human Nardilysin (NRDC) activation kit by CRISPRa

SKU GA103270

NRDC CRISPRa kit - CRISPR gene activation of human nardilysin convertase

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: NRDC
• Locus ID: 4898
• Components:

  GA103270G1, Nardilysin gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103270G2, Nardilysin gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103270G3, Nardilysin gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001101662, NM_001242361, NM_002525
• UniProt ID: O43847
• Synonyms: hNRD1; hNRD2; NRD1
• Summary: This gene encodes a zinc-dependent endopeptidase that cleaves peptide substrates at the N-terminus of arginine residues in dibasic moieties and is a member of the peptidase M16 family. This protein interacts with heparin-binding EGF-like growth factor and plays a role in cell migration and proliferation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011]