OriGene Logo

Customer Login

Checkout as a new customer

Creating an account has many benefits:

  • See order and shipping status
  • Track order history
  • Check out faster
Create an Account

Human NOTCH3 activation kit by CRISPRa

Be the first to review this product
SKU
GA103241
NOTCH3 CRISPRa kit - CRISPR gene activation of human notch receptor 3
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA371188 NOTCH3 rabbit polyclonal antibody
100 ul
$310.00
RC224711 NOTCH3 (Myc-DDK-tagged)-Human notch 3 (NOTCH3)
10 ug
$2,873.00

Other products for "NOTCH3"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol NOTCH3
Locus ID 4854
Components

GA103241G1, NOTCH3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA103241G2, NOTCH3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA103241G3, NOTCH3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_000435
UniProt ID Q9UM47
Synonyms CADASIL; CADASIL1; CASIL; IMF2; LMNS
Summary This gene encodes the third discovered human homologue of the Drosophilia melanogaster type I membrane protein notch. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signalling pathway that plays a key role in neural development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remains to be determined. Mutations in NOTCH3 have been identified as the underlying cause of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL). provided by RefSeq, Jul 2008
Reviews
Write Review
 
 
 
 
 

Be the first to review this product

Please note:
Only reviews with images are eligible for a $20/20€ Amazon gift card.
Reviews without images are eligible for a $10/10€ Amazon gift card.
For more details about the terms and conditions, please visit the promotion page.

Review image
Documents
Resources
Other Versions
SKU Description Size Price
KN224711 NOTCH3 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN224711BN NOTCH3 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN224711LP NOTCH3 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN224711RB NOTCH3 - human gene knockout kit via CRISPR, HDR mediated 1 kit
$1,657.00
KN424711 NOTCH3 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

file-alt Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Related Products